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KMID : 1022820130040010007
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Journal of Multiple Sclerosis and Neuroimmunology
2013 Volume.4 No. 1 p.7 ~ p.12
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Systemic Autoimmunity and Idiopathic Inflammatory Demyelinating Diseases of the Central Nervous System (IIDDs)
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Yang Ji-Won
Kim Sung-Min
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Abstract
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Idiopathic inflammatory demyelinating disease (IIDDs) is a disease entity containing multiple sclerosis (MS), neuromyelitis optica (NMO), transverse myelitis, optic neuritis and so on. Many recent studies revealed that there might be a common pathomechanism between IIDDs and systemic autoimmune diseases. Here we provide a general overview for the evidence of systemic autoimmunity in the NMO and MS, and provide a possible hypothesis for this phenomenon.
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KEYWORD
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Neuromyelitis optica, Multiple sclerosis, Autoimmune disease
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